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18。 As suggested by both referees; a discussion of the possibility of laser action on chromosome has been included (page16; paragraph 2)。
19。 We included a new set of photographs with better definition than those originally submitted and to which a scale has been added。
20。 Following the suggestion of the referees; we have redraw Figure 3 and 4。
21。 Two further papers; published since our original submission; have been added to the text and Reference section。 These are:
22。 We should like to thank the referees for their helpful ments and hope that we have now produced a more balance and better account of our work。 We trust that the revised manuscript is acceptable for publication。
23。 I greatly appreciate both your help and that of the referees concerning improvement to this paper。 I hope that the revised manuscript is now suitable for publication。
24。 I should like to express my appreciation to you and the referees for suggesting how to improve our paper。
25。 I apologize for the delay in revising the manuscript。 This was due to our doing an additional experiment; as suggested by referees。